ISDA: 9Y3F

Deposition Date 2025-09-02

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

9Y3F

Keywords:

GENE REGULATION, HYDROLASE/DNA BINDING PROTEIN/DNA

Title:

Extended cryo-EM structure of human SRCAP-CFDP1-nucleosome complex in the poised state

Biological Source:

Source Organism(s):

Xenopus laevis (Taxon ID: 8355)
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.50 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Helicase SRCAP
Chain IDs:O (auth: A)
Chain Length:3230
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Vacuolar protein sorting-asso
Chain IDs:P (auth: B)
Chain Length:364
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Actin-related protein 6
Chain IDs:A (auth: C)
Chain Length:396
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Zinc finger HIT domain-contai
Chain IDs:Q (auth: D)
Chain Length:154
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:RuvB-like 2
Chain IDs:B (auth: F), S (auth: H), U (auth: J)
Chain Length:463
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:RuvB-like 1
Chain IDs:C (auth: G), R (auth: E), T (auth: I)
Chain Length:456
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Actin-like protein 6A
Chain IDs:V (auth: K), X (auth: M)
Chain Length:429
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Actin, cytoplasmic 1
Chain IDs:W (auth: L)
Chain Length:375
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:DNA methyltransferase 1-assoc
Chain IDs:D (auth: N)
Chain Length:467
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Craniofacial development prot
Chain IDs:Y (auth: P)
Chain Length:299
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1
Chain IDs:E (auth: Q), G (auth: S)
Chain Length:128
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H2B 1.1
Chain IDs:F (auth: R), H (auth: T)
Chain Length:125
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H3.2
Chain IDs:I (auth: U), K (auth: W)
Chain Length:135
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:J (auth: V), L (auth: X)
Chain Length:102
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (285-MER)
Chain IDs:M (auth: Y)
Chain Length:285
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (285-MER)
Chain IDs:N (auth: Z)
Chain Length:285
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules