ISDA: 9Y3E

Deposition Date 2025-09-02

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

9Y3E

Keywords:

GENE REGULATION, HYDROLASE/DNA BINDING PROTEIN/DNA

Title:

Extended cryo-EM structure of human SRCAP-nucleosome complex in the pre-engaged state

Biological Source:

Source Organism(s):

Xenopus laevis (Taxon ID: 8355)
synthetic construct (Taxon ID: 32630)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

5.00 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Helicase SRCAP
Chain IDs:A
Chain Length:3230
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Vacuolar protein sorting-asso
Chain IDs:B
Chain Length:364
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Actin-related protein 6
Chain IDs:C
Chain Length:396
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Zinc finger HIT domain-contai
Chain IDs:D
Chain Length:154
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:RuvB-like 1
Chain IDs:E, G, I
Chain Length:456
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:RuvB-like 2
Chain IDs:F, H, J
Chain Length:463
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Actin-like protein 6A
Chain IDs:K, M
Chain Length:429
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Actin, cytoplasmic 1
Chain IDs:L
Chain Length:375
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:DNA methyltransferase 1-assoc
Chain IDs:N
Chain Length:467
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1
Chain IDs:O (auth: Q), Q (auth: S)
Chain Length:128
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H2B 1.1
Chain IDs:P (auth: R), R (auth: T)
Chain Length:125
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H3.2
Chain IDs:S (auth: U), U (auth: W)
Chain Length:135
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:T (auth: V), V (auth: X)
Chain Length:102
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (285-MER)
Chain IDs:W (auth: Y)
Chain Length:285
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (285-MER)
Chain IDs:X (auth: Z)
Chain Length:285
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules