9XZB image
Deposition Date 2025-08-27
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
9XZB
Keywords:
LIGASE
Title:
E3 ubiquitin-protein ligase CBL-B in complex with compound 2
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.75 Å
R-Value Free:
0.22
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
P 21 21 21
9XZB validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:E3 ubiquitin-protein ligase C
Gene (Uniprot):CBLB
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q13191 Pfam ID:PF02262, PF02761, PF02762, PF00097 EC:2.3.2.27
Ligand Molecules
CA
XM3
ZN
Primary Citation
Discovery and characterization of Cbl-b intra-molecular inhibitory glues with biological activity.
To Be Published ? ? ? (?)
Primary Citation of related structures
9XZB
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