9XS7 image
Deposition Date 2025-11-20
Release Date 2026-08-12
Last Version Date 2026-08-12
Entry Detail
PDB ID:
9XS7
Keywords:
OXIDOREDUCTASE
Title:
Factor inhibiting HIF-1 alpha in complex with Mn(II) and rhein
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.51 Å
R-Value Free:
0.23
R-Value Work:
0.18
R-Value Observed:
0.19
Space Group:
P 41 21 2
9XS7 validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Hypoxia-inducible factor 1-al
Chain IDs:A
Chain Length:349
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
MN
RHN
Primary Citation
Structural Insights into Metal-Chelating Natural Inhibitors of Factor Inhibiting HIF-1 alpha.
J.Nat.Prod. ? ? ? (2026)
PMID: 42455177 DOI: 10.1021/acs.jnatprod.6c00734
Primary Citation of related structures
9XS7
Feedback Form
Name
Email
Institute
Feedback