ISDA: 9XMM

Deposition Date 2025-11-11

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9XMM

Keywords:

CELL ADHESION

Title:

Cryo-EM structure of Integrin alpha V beta 6 complex with a bicyclic inhibitory peptide

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.88 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Integrin alpha-V heavy chain
Gene (Uniprot):ITGAV
Chain IDs:A
Chain Length:595
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P06756 Pfam ID:PF01839, PF08441

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Integrin beta-6
Gene (Uniprot):ITGB6
Mutagens:I270C
Chain IDs:B
Chain Length:474
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P18564 Pfam ID:PF17205, PF00362, PF18372

Polymer Type:polypeptide(L)
Molecule:ALA-TRP-ARG-GLY-ASP-CHG-CYS-A
Chain IDs:C (auth: E)
Chain Length:9
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules