ISDA: 9XME

Deposition Date 2025-11-10

Release Date 2026-09-23

Last Version Date 2026-09-30

Entry Detail

PDB ID:

9XME

Keywords:

IMMUNE SYSTEM

Title:

Complex of HLA-A2, a class I MHC, with a wild type UTP20 peptide

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli, Chemical production metagenome

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.04 Å

R-Value Free:

0.24

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:MHC class I antigen
Gene (Uniprot):HLA-A
Chain IDs:A, D
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q8WLS4

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Gene (Uniprot):B2M
Chain IDs:B, E
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P61769 Pfam ID:PF07654

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small subunit processome comp
Gene (Uniprot):UTP20
Chain IDs:C, F
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O75691

Primary Citation

Structural basis for CD8 + T cell recognition of the charge-reversed neoantigen UTP20 D2661H .

Wang, J, Li, S, Mao, L, Yang, D, Yao, Z, Shi, J, He, W, Wu, D.Show

J.Struct.Biol. 218 108371 108371 (2026)

PMID: 42727733 DOI: 10.1016/j.jsb.2026.108371

Primary Citation of related structures

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