ISDA: 9XIY

Deposition Date 2025-11-04

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

9XIY

Keywords:

SIGNALING PROTEIN

Title:

Structure of the CX3CL1.44-US28-GqiN18-scFv16 in the T2C-state

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)
Cytomegalovirus (Taxon ID: 10358)

Expression System(s):

Trichoplusia ni, Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.86 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAQ
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P50148 Pfam ID:PF00503 EC:3.6.5.-

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF25391

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Polymer Type:polypeptide(L)
Molecule:antibody fragment scFv16
Chain IDs:D
Chain Length:0
Number of Molecules:1
Biological Source:Mus musculus

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Processed fractalkine
Gene (Uniprot):CX3CL1
Mutagens:residues 1-7 QHHGVTK replaced with VRPHINN
Chain IDs:E (auth: L)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P78423 Pfam ID:PF00048

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:G-protein coupled receptor ho
Gene (Uniprot):US28
Chain IDs:F (auth: R)
Chain Length:0
Number of Molecules:1
Biological Source:Cytomegalovirus

UniProt ID:P69332

Ligand Molecules

GDP

Primary Citation

Structural basis of a stepwise Gq activation by a chemokine receptor US28

Jude, K.M, Tsutsumi, N.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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