ISDA: 9XI9

Deposition Date 2025-11-02

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

9XI9

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM

Title:

SARS-CoV-2 Omicron LP.8.1 spike trimer (S-6P) in complex with 3 ZL58 Fabs and 3 ZL525 Fabs, focused refinement of RBD and Fab region

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.93 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Heavy chain of ZL525 Fab
Chain IDs:A
Chain Length:228
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Light chain of ZL525 Fab
Chain IDs:B
Chain Length:217
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Spike protein S1
Chain IDs:D (auth: C)
Chain Length:195
Number of Molecules:1
Biological Source:Severe acute respiratory syndrome coronavirus 2

Polymer Type:polypeptide(L)
Molecule:Heavy chain of ZL58 Fab
Chain IDs:C (auth: H)
Chain Length:221
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Light chain of ZL58 Fab
Chain IDs:E (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

AI identifies Elite Antibodies that Tolerate Escape Mutations from a Population Antibody Class Exerting Continued Selection Over SARS-CoV-2

Niu, C, Huang, X, Yan, Q, Liu, B, Gao, X, Song, Y, Wang, J, Wang, L, Li, Z, Zheng, H, He, P, Huang, X, Yuan, H, Zou, B, Yang, Y, Wu, F, Yao, Y, Chen, X, Chen, L, He, J, Yao, J, Zhao, J, Xiong, X.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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