ISDA: 9XI0

Deposition Date 2025-11-02

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

9XI0

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM/HYDROLASE

Title:

SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C092 Fab and ACE2 (3 RBD up)

Biological Source:

Source Organism(s):

Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.98 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Spike glycoprotein
Chain IDs:A, B, C
Chain Length:1247
Number of Molecules:3
Biological Source:Severe acute respiratory syndrome coronavirus 2

Polymer Type:polypeptide(L)
Molecule:Processed angiotensin-convert
Chain IDs:F (auth: E), I (auth: F), L (auth: D)
Chain Length:602
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Heavy chain of C092 Fab
Chain IDs:D (auth: H), G, J (auth: I)
Chain Length:228
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Light chain of C092 Fab
Chain IDs:E (auth: L), H (auth: J), K
Chain Length:217
Number of Molecules:3
Biological Source:Homo sapiens

Ligand Molecules

NAG

Primary Citation

AI identifies Elite Antibodies that Tolerate Escape Mutations from a Population Antibody Class Exerting Continued Selection Over SARS-CoV-2

Niu, C, Huang, X, Yan, Q, Liu, B, Gao, X, Song, Y, Wang, J, Wang, L, Li, Z, Zheng, H, He, P, Huang, X, Yuan, H, Zou, B, Yang, Y, Wu, F, Yao, Y, Chen, X, Chen, L, He, J, Yao, J, Zhao, J, Xiong, X.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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