9XHR image
Deposition Date 2025-11-02
Release Date 2026-05-06
Last Version Date 2026-05-06
Entry Detail
PDB ID:
9XHR
Keywords:
PEPTIDE BINDING PROTEIN
Title:
Crystal Structure of Human Cathepsin B with a D-peptide substrate
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Mammalian expression vector bsrgi-mcs-pcdna3.1
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.50 Å
R-Value Free:
0.16
R-Value Work:
0.14
R-Value Observed:
0.14
Space Group:
P 21 21 21
9XHR validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cathepsin B
Gene (Uniprot):CTSB
Mutagens:S115A
Chain IDs:A
Chain Length:255
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P07858 Pfam ID:PF00112 EC:3.4.22.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(D)
Molecule:ACE-DAR-DLY-DTY-DTY-GLY-0QE
Chain IDs:B (auth: C)
Chain Length:7
Number of Molecules:1
Biological Source:synthetic construct
Primary Citation
Transcending stereochemical boundaries: ambidextrous cleavage of D- and L-peptide enantiomers by natural eukaryotic proteases
Vita ? ? ? (2026)
DOI: 10.15302/vita.2026.03.0022
Primary Citation of related structures
9XHR
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