9XHI image
Deposition Date 2025-11-01
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9XHI
Keywords:
MEMBRANE PROTEIN
Title:
Structure of the CCL21-CCR7-Gi-scFv16 complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)
Expression System(s):
Homo sapiens, Trichoplusia ni
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9XHI validation report
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2, GNAI1
Chain IDs:C (auth: A), E (auth: C)
Chain Length:432
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P59768,P63097 Pfam ID:PF00631, PF00503
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:D (auth: B)
Chain Length:371
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62873 Pfam ID:PF25391
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody fragment scFv16
Chain IDs:F (auth: D)
Chain Length:256
Number of Molecules:1
Biological Source:Mus musculus
UniProt ID:9XHI
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:C-C motif chemokine 21
Gene (Uniprot):CCL21
Chain IDs:A (auth: L)
Chain Length:126
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O00585 Pfam ID:PF00048
Protein Blast
Polymer Type:polypeptide(L)
Molecule:C-C chemokine receptor type 7
Gene (Uniprot):CCR7
Chain IDs:B (auth: R)
Chain Length:551
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P32248,A0A482LYE4 Pfam ID:PF00001
Ligand Molecules
CLR
Primary Citation
Structural Insights into Biased Signaling at the Chemokine Receptor CCR7
To Be Published ? ? ? (?)
Primary Citation of related structures
9XHI
Feedback Form
Name
Email
Institute
Feedback