ISDA: 9XG7

Deposition Date 2025-10-29

Release Date 2026-05-27

Last Version Date 2026-05-27

Entry Detail

PDB ID:

9XG7

Keywords:

VIRAL PROTEIN

Title:

The crystal structure of MERS-CoV Main protease in complex with inhibitor FD2-21

Biological Source:

Source Organism(s):

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.53 Å

R-Value Free:

0.29

R-Value Work:

0.24

R-Value Observed:

0.25

Space Group:

P 1 21 1

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:3C-like proteinase nsp5
Gene (Uniprot):rep
Chain IDs:A, B, C, D
Chain Length:304
Number of Molecules:4
Biological Source:Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)

UniProt ID:K9N7C7 Pfam ID:PF05409 EC:3.4.22.-

Ligand Molecules

A1EZ7

Primary Citation

The crystal structure of MERS-CoV Main protease in complex with inhibitor FD2-21

To Be Published ? ? ? (?)

Primary Citation of related structures