ISDA: 9XDR

Deposition Date 2025-10-27

Release Date 2026-07-08

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9XDR

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of asimadoline-BMS-986187-bound KOR-Gi1 complex

Biological Source:

Source Organism(s):

Oplophorus gracilirostris (Taxon ID: 727944)
Homo sapiens (Taxon ID: 9606)
Escherichia coli (Taxon ID: 562)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.58 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Chain IDs:A
Chain Length:354
Number of Molecules:1
Biological Source:Oplophorus gracilirostris

UniProt ID:P63097 Pfam ID:PF00503 EC:3.6.5.-

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:384
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Soluble cytochrome b562,Kappa
Gene (Uniprot):cybC, OPRK1
Chain IDs:D (auth: R)
Chain Length:608
Number of Molecules:1
Biological Source:Escherichia coli, Homo sapiens, synthetic construct

UniProt ID:P0ABE7,P41145 Pfam ID:PF00001

Ligand Molecules