ISDA: 9XCA

Deposition Date 2025-10-25

Release Date 2026-03-18

Last Version Date 2026-09-30

Entry Detail

PDB ID:

9XCA

Keywords:

TRANSPORT PROTEIN

Title:

CryoEM structure of the G6PT dimer

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.27 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Glucose-6-phosphate exchanger
Gene (Uniprot):SLC37A4
Chain IDs:A (auth: B), B (auth: C)
Chain Length:452
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O43826 Pfam ID:PF07690

Ligand Molecules

LMN

Primary Citation

Structures of the human glucose-6-phosphate transporter provide insights into its transport cycle and substrate recognition.

Zhang, W, Jiao, H, Xue, J, Zhou, J, Wang, Y, Pan, Q, Guo, Y, Zhang, G, Hu, H, Guo, X.Show

Plos Biol. 24 e3003731 e3003731 (2026)

PMID: 41911224 DOI: 10.1371/journal.pbio.3003731

Primary Citation of related structures

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