9XC6 image
Deposition Date 2025-10-25
Release Date 2026-07-08
Last Version Date 2026-07-08
Entry Detail
PDB ID:
9XC6
Title:
Cryo-EM structure of BMS-986187-bound MOR-Gi1 complex
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.04 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:A
Chain Length:353
Number of Molecules:1
Biological Source:Oplophorus gracilirostris
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:B
Chain Length:335
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:C
Chain Length:56
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Mu-type opioid receptor
Chain IDs:D (auth: R)
Chain Length:281
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Molecular mechanism of allosteric modulation of opioid receptors.
Signal Transduct Target Ther 11 ? ? (2026)
PMID: 42362532 DOI: 10.1038/s41392-026-02759-5
Primary Citation of related structures
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