9XAR image
Deposition Date 2025-10-23
Release Date 2026-08-05
Last Version Date 2026-09-16
Entry Detail
PDB ID:
9XAR
Keywords:
Title:
Structure of the SARS-CoV-2 Spike N-terminal domain(NTD) in complex with the C1624 Fab
Biological Source:
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.77 Å
R-Value Free:
0.28
R-Value Work:
0.23
R-Value Observed:
0.24
Space Group:
P 1 21 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Spike protein S1
Gene (Uniprot):S
Chain IDs:A, F (auth: D)
Chain Length:298
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2
Polymer Type:polypeptide(L)
Molecule:C1624 heavy chain
Chain IDs:B, D (auth: E)
Chain Length:236
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:C1624 light chain
Chain IDs:C, E (auth: F)
Chain Length:218
Number of Molecules:2
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
A structural and mechanistic atlas of NTD antibody neutralization and immune escape across SARS-CoV-2 prototype and its (sub-)variants.
Proc.Natl.Acad.Sci.USA 123 e2535385123 e2535385123 (2026)
PMID: 42555640 DOI: 10.1073/pnas.2535385123
Primary Citation of related structures
Feedback Form
Name
Email
Institute
Feedback