ISDA: 9X2K

Deposition Date 2025-10-05

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9X2K

Keywords:

LYASE

Title:

AARS1 bound with XY353 and Gly-SA

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.71 Å

R-Value Free:

0.21

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Alanine--tRNA ligase, cytopla
Gene (Uniprot):AARS1
Chain IDs:A
Chain Length:384
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P49588 Pfam ID:PF01411 EC:6.1.1.7,6.-.-.-

Ligand Molecules

A1EYX

G5A

GOL

Primary Citation

Covalent Allosteric Inhibition of AARS1 Lactyltransferase

Huang, Y, Liu, S, Min, J.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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