ISDA: 9WXH

Deposition Date 2025-09-25

Release Date 2026-06-24

Last Version Date 2026-06-24

Entry Detail

PDB ID:

9WXH

Keywords:

IMMUNE SYSTEM

Title:

Cryo-EM structure of the type III-D2 CRISPR-Cas effector complex bound to a cognate target RNA in the pre-cleavage state

Biological Source:

Source Organism(s):

Gammaproteobacteria bacterium (Taxon ID: 1913989)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polyribonucleotide
Molecule:CRISPR RNA
Chain IDs:A
Chain Length:43
Number of Molecules:1
Biological Source:Gammaproteobacteria bacterium

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cas10
Chain IDs:B
Chain Length:592
Number of Molecules:1
Biological Source:Gammaproteobacteria bacterium

UniProt ID:A0A9D0P2E0

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:CRISPR type III-associated pr
Chain IDs:C
Chain Length:635
Number of Molecules:1
Biological Source:Gammaproteobacteria bacterium

UniProt ID:A0A9D0P213

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:TIGR03986 family CRISPR-assoc
Chain IDs:D
Chain Length:1235
Number of Molecules:1
Biological Source:Gammaproteobacteria bacterium

UniProt ID:A0A9D0P2B2

Polymer Type:polyribonucleotide
Molecule:Cognate target RNA (CTR)
Chain IDs:E
Chain Length:47
Number of Molecules:1
Biological Source:Gammaproteobacteria bacterium

Ligand Molecules