ISDA: 9WX2

Deposition Date 2025-09-24

Release Date 2026-07-08

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9WX2

Keywords:

IMMUNE SYSTEM

Title:

Crystal structure of the HEPN domain of Dandelion

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.55 Å

R-Value Free:

0.20

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Dandelion-hepn
Chain IDs:A, B
Chain Length:163
Number of Molecules:2
Biological Source:Escherichia coli

Ligand Molecules

Primary Citation

Oligomer disassembly activates an HEPN-containing bacterial defense system.

Tang, Y, Liu, T, Xiong, C, Chen, Q, Yu, Y.Show

Mol.Cell 86 2560 ? (2026)

PMID: 42349403 DOI: 10.1016/j.molcel.2026.06.008

Primary Citation of related structures

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