ISDA: 9WWL

Deposition Date 2025-09-24

Release Date 2026-09-30

Last Version Date 2026-09-30

Entry Detail

PDB ID:

9WWL

Keywords:

GENE REGULATION/DNA

Title:

Cryo-EM structure of transcription activation complex with DevR from Mycobacterium tuberculosis

Biological Source:

Source Organism(s):

Mycobacterium tuberculosis H37Rv (Taxon ID: 83332)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.00 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpoA
Chain IDs:A, B, I (auth: G)
Chain Length:0
Number of Molecules:3
Biological Source:Mycobacterium tuberculosis H37Rv

UniProt ID:P9WGZ1 Pfam ID:PF01193, PF01000, PF03118 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpoB
Chain IDs:C
Chain Length:0
Number of Molecules:1
Biological Source:Mycobacterium tuberculosis H37Rv

UniProt ID:P9WGY9 Pfam ID:PF04563, PF04561, PF04565, PF10385, PF00562, PF04560 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpoC
Chain IDs:D
Chain Length:0
Number of Molecules:1
Biological Source:Mycobacterium tuberculosis H37Rv

UniProt ID:P9WGY7 Pfam ID:PF04997, PF00623, PF04983, PF05000, PF04998 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpoZ
Chain IDs:H (auth: E)
Chain Length:0
Number of Molecules:1
Biological Source:Mycobacterium tuberculosis H37Rv

UniProt ID:P9WGY5 Pfam ID:PF01192 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:RNA polymerase sigma factor S
Gene (Uniprot):sigA
Chain IDs:E (auth: F)
Chain Length:0
Number of Molecules:1
Biological Source:Mycobacterium tuberculosis H37Rv

UniProt ID:P9WGI1 Pfam ID:PF00140, PF04542, PF04539, PF04545 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-binding transcriptional a
Gene (Uniprot):devR
Chain IDs:J (auth: I), K (auth: J)
Chain Length:0
Number of Molecules:2
Biological Source:Mycobacterium tuberculosis H37Rv

UniProt ID:P9WMF9 Pfam ID:PF00072, PF00196

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (124-MER)
Chain IDs:F (auth: O)
Chain Length:0
Number of Molecules:1
Biological Source:Mycobacterium tuberculosis H37Rv

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (124-MER)
Chain IDs:G (auth: P)
Chain Length:0
Number of Molecules:1
Biological Source:Mycobacterium tuberculosis H37Rv

Ligand Molecules

Primary Citation

Cryo-EM structure of transcription activation complex with DevR from Mycobacterium tuberculosis

Lin, W, Shi, J.Show

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Primary Citation of related structures

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