ISDA: 9WVY

Deposition Date 2025-09-22

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9WVY

Keywords:

OXIDOREDUCTASE

Title:

NDP-4-keto-6-deoxyglucose-3-dehydratase KsgR in complex with PMP and AKG

Biological Source:

Source Organism(s):

Streptomyces microaureus (Taxon ID: 1689400)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.30 Å

R-Value Free:

0.25

R-Value Work:

0.24

Space Group:

I 21 3

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Putative NDP-4-keto-6-deoxygl
Gene (Uniprot):kasR
Chain IDs:A
Chain Length:399
Number of Molecules:1
Biological Source:Streptomyces microaureus

UniProt ID:A0A0K1H368

Ligand Molecules

AKG

PMP

Primary Citation

Characterization of UDP-Sugar 3-Dehydrase KsgR in the Biosynthesis of a Distinctive Multideoxy Diamino-Sugar Kasugamine of Kasugamycin.

Li, Y, Chen, Y, Shi, J, Wu, J, Wang, Y, Ren, J, Li, Y, Zhou, J, Gao, Q, Mei, K, Guo, Z.Show

J.Am.Chem.Soc. 148 19205 19213 (2026)

PMID: 42076866 DOI: 10.1021/jacs.6c03331

Primary Citation of related structures

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