ISDA: 9WUQ

Deposition Date 2025-09-18

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9WUQ

Keywords:

ISOMERASE

Title:

Crystal structure of human L-PGDS in complex with covalently bound 15d-PGJ2

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.53 Å

R-Value Free:

0.26

R-Value Work:

0.23

R-Value Observed:

0.24

Space Group:

P 1

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Prostaglandin-H2 D-isomerase
Chain IDs:A, B, C, D
Chain Length:169
Number of Molecules:4
Biological Source:Homo sapiens

Ligand Molecules

A1MCB

IOD

Primary Citation

Integrative Real-Time NMR and X-ray Crystallography Reveal Prostaglandin D 2 Metabolism.

Ohta, S, Shimamoto, S, Oda, H, Ohkubo, T, Oki, H, Shiraishi, Y, Kawahara, K, Yoshida, T, Ueda, T.Show

Anal.Chem. 97 27608 27620 (2025)

PMID: 41355430 DOI: 10.1021/acs.analchem.5c03604

Primary Citation of related structures

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