ISDA: 9WS6

Deposition Date 2025-09-12

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

9WS6

Keywords:

TRANSFERASE

Title:

Crystal structure of AMP-PNP-bound PAK2 kinase domain containing D368N mutant

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.22

R-Value Work:

0.19

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:PAK-2p34
Gene (Uniprot):PAK2
Mutagens:D368N
Chain IDs:A, B, C, D
Chain Length:323
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q13177 Pfam ID:PF00069 EC:2.7.11.1

Ligand Molecules

ANP

Primary Citation

Kinetic and structural insights into the autoactivation of PAK2 kinase domain: A research paradigm for studying self-activating enzyme

Chen, F.Y, Hu, H.-F, Wang, J, Luo, Z.P, Wu, J.-W, Wang, Z.-X.Show

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