9WPX image
Deposition Date 2025-09-10
Release Date 2026-09-16
Last Version Date 2026-09-16
Entry Detail
PDB ID:
9WPX
Keywords:
SIGNALING PROTEIN/IMMUNE SYSTEM
Title:
5-HT2AR bound to IHCH-1904 in complex with mini-Gq and scFv16 obtained by cryo-electron microscopy (cryoEM)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.10 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9WPX validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:5-hydroxytryptamine receptor
Gene (Uniprot):HTR2A
Chain IDs:A
Chain Length:339
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P28223 Pfam ID:PF00001
Polymer Type:polypeptide(L)
Molecule:G protein subunit q (Gi2-mini
Chain IDs:B
Chain Length:246
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:D (auth: C)
Chain Length:340
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62873 Pfam ID:PF25391
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C (auth: D)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P59768 Pfam ID:PF00631
Polymer Type:polypeptide(L)
Molecule:single-chain variable fragmen
Chain IDs:E
Chain Length:287
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
A1EYI
Primary Citation
Structure-based design of subtype-selective psychedelic analogues
To Be Published ? ? ? (?)
Primary Citation of related structures
9WPX
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