ISDA: 9WP2

Deposition Date 2025-09-08

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

9WP2

Keywords:

HYDROLASE

Title:

E.coli beta-galactosidase in complex with fluorescent probe KSS6

Biological Source:

Source Organism(s):

Escherichia coli (strain K12) (Taxon ID: 83333)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.45 Å

R-Value Free:

0.26

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-galactosidase
Gene (Uniprot):lacZ
Chain IDs:A, B, C, D
Chain Length:1025
Number of Molecules:4
Biological Source:Escherichia coli (strain K12)

UniProt ID:P00722 Pfam ID:PF02837, PF00703, PF02836, PF16353, PF02929 EC:3.2.1.23

Ligand Molecules

A1EX8

Primary Citation

Identification of Senescence-Associated beta-Galactosidase With Single-Molecule Resolution

Wang, G, Chen, X, Ge, Y, Duan, K, Wu, S, Qiao, Q, Shi, D, Shen, J.W, Zhang, J, James, T.D, Xu, Z, Guo, Y.Show

Angew.Chem.Int.Ed.Engl. n/a ? ? (2026)

DOI: 10.1002/anie.5443283

Primary Citation of related structures

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