9WND image
Deposition Date 2025-09-04
Release Date 2026-09-09
Last Version Date 2026-09-09
Entry Detail
PDB ID:
9WND
Keywords:
MEMBRANE PROTEIN
Title:
5HT2AR-miniGq heterotrimer in complex with a psychedelic psilocin
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9WND validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:5-hydroxytryptamine receptor
Gene (Uniprot):HTR2A
Chain IDs:A
Chain Length:337
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P28223 Pfam ID:PF00001
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAS, GNG2
Chain IDs:B
Chain Length:326
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P59768,Q5JWF2 Pfam ID:PF00631, PF00503 EC:3.6.5.-
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:C
Chain Length:340
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62873 Pfam ID:PF25391
Polymer Type:polypeptide(L)
Molecule:single-chain variable fragmen
Chain IDs:D
Chain Length:258
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
91Q
Primary Citation
Mechanistic Basis for 5-HT2AR Over 5-HT2BR Activation
To Be Published ? ? ? (?)
Primary Citation of related structures
9WND
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