ISDA: 9WG4

Deposition Date 2025-08-22

Release Date 2026-06-17

Last Version Date 2026-06-17

Entry Detail

PDB ID:

9WG4

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of pocket engineered OR52cs in its active state

Biological Source:

Source Organism(s):

Lama glama (Taxon ID: 9844)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli, Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.29 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nanobody 35
Chain IDs:A (auth: N)
Chain Length:130
Number of Molecules:1
Biological Source:Lama glama

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Pocket engineered human conse
Chain IDs:B (auth: R)
Chain Length:323
Number of Molecules:1
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:mini form Guanine nucleotide-
Chain IDs:C (auth: X)
Chain Length:248
Number of Molecules:1
Biological Source:Homo sapiens

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:D (auth: Y)
Chain Length:358
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:E (auth: Z)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Ligand Molecules

A1MBN

Primary Citation

The structure of pocket engineered OR52cs in its active state

Choi, C.W, Choi, H.-J.Show

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Primary Citation of related structures

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