ISDA: 9WCG

Deposition Date 2025-08-17

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

9WCG

Keywords:

VIRAL PROTEIN

Title:

Crystal Structure of SARS Coronavirus Main Proteinase in Complex with a Broad-spectrum Inhibitor

Biological Source:

Source Organism(s):

SARS coronavirus Urbani (Taxon ID: 228330)

Expression System(s):

Escherichia coli bl21

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.39 Å

R-Value Free:

0.33

R-Value Work:

0.27

R-Value Observed:

0.27

Space Group:

C 1 2 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:SARS-CoV 3CLpro
Chain IDs:A (auth: B)
Chain Length:300
Number of Molecules:1
Biological Source:SARS coronavirus Urbani

Ligand Molecules

A1EYZ

Primary Citation

Harnessing AI, Structural Biology, and Medicinal Chemistry to Overcome Viral Diversity: Broad-Spectrum 3C/3CL Protease Inhibitors Effective Across Pisoniviricetes

Liu, l, Wang, j.l, Wang, s.h, Dai, w.h, Zhang, x.l, Bai, f, Liu, h.Show

To Be Published ? ? ? (?)

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