ISDA: 9WB2

Deposition Date 2025-08-13

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

9WB2

Keywords:

ONCOPROTEIN

Title:

Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Compound No.33 and GRIP Peptide

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.95 Å

R-Value Free:

0.23

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

C 2 2 21

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Estrogen receptor
Mutagens:Y537S
Chain IDs:A (auth: B), C (auth: A)
Chain Length:254
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:GRIP Peptide
Chain IDs:B (auth: D), D (auth: C)
Chain Length:8
Number of Molecules:2
Biological Source:Homo sapiens

Ligand Molecules