9WAK image
Deposition Date 2025-08-12
Release Date 2026-05-27
Last Version Date 2026-05-27
Entry Detail
PDB ID:
9WAK
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of a human sodium pump W931R mutant in ouabain-bound E2P state
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.86 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9WAK validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Sodium/potassium-transporting
Gene (Uniprot):ATP1A1
Mutagens:W931R
Chain IDs:A
Chain Length:985
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P05023 Pfam ID:PF00690, PF00122, PF13246, PF00689 EC:7.2.2.3
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Sodium/potassium-transporting
Gene (Uniprot):ATP1B1
Chain IDs:B
Chain Length:303
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P05026 Pfam ID:PF00287
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
BFD A ASP modified residue
Ligand Molecules
CLR
MG
NA
OBN
Primary Citation
Passive aberrant currents are induced by all Na pump variants causing hypomagnesemia
To Be Published ? ? ? (?)
Primary Citation of related structures
9WAK
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