ISDA: 9WA8

Deposition Date 2025-08-11

Release Date 2026-07-08

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9WA8

Keywords:

IMMUNE SYSTEM

Title:

Crystal structure of AcrIIA19 from Staphylococcus pseudintermedius

Biological Source:

Source Organism(s):

Staphylococcus pseudintermedius (Taxon ID: 283734)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.98 Å

R-Value Free:

0.27

R-Value Work:

0.23

R-Value Observed:

0.24

Space Group:

C 2 2 21

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Anti-CRISPR protein
Chain IDs:A, B, C, D
Chain Length:123
Number of Molecules:4
Biological Source:Staphylococcus pseudintermedius

Primary Citation

AcrIIA19 binds to the WED domain and inhibits various Cas9 orthologs at multiple stages.

Kim, G.E, Lee, S.Y, Kang, Y.J, Bin Jin, H, Park, H.H.Show

Commun Biol 9 136 136 (2025)

PMID: 41430372 DOI: 10.1038/s42003-025-09417-6

Primary Citation of related structures

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