ISDA: 9WA5

Deposition Date 2025-08-11

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9WA5

Keywords:

VIRAL PROTEIN

Title:

Crystal structure of an inactive form of NS2B-NS3 Protease

Biological Source:

Source Organism(s):

Zika virus (Taxon ID: 64320)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.40 Å

R-Value Free:

0.24

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

P 41 21 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Serine protease subunit NS2B,
Chain IDs:A, B
Chain Length:213
Number of Molecules:2
Biological Source:Zika virus

UniProt ID:Q32ZE1 Pfam ID:PF00949 EC:2.7.7.48

Ligand Molecules

EDO

Primary Citation

An inactive Zika NS2B-NS3pro protease construct for investigating allosteric inhibitors.

Ngo, K.H, Lattmann, S, Anindita, P.D, Liew, C.W, Harris, R.S, Luo, D, Kang, C.Show

J. Struct. Biol. 218 108314 108314 (2026)

PMID: 41833763 DOI: 10.1016/j.jsb.2026.108314

Primary Citation of related structures

Feedback Form