ISDA: 9W6X

Deposition Date 2025-08-05

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9W6X

Keywords:

TRANSFERASE

Title:

Crystal Structure of YtkW in Complex with SAM

Biological Source:

Source Organism(s):

Streptomyces sp. TP-A2060 (Taxon ID: 991125)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.38 Å

R-Value Free:

0.25

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

I 41 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:YtkW
Chain IDs:A
Chain Length:199
Number of Molecules:1
Biological Source:Streptomyces sp. TP-A2060

UniProt ID:I3NN71

Ligand Molecules

SAM

Primary Citation

S-Methyl Thioester Formation Uncovers Early Biosynthetic Steps of Yatakemycin.

Feng, J, Wang, S, Yang, X, Tian, T, Huang, W, Teng, X, Pan, H.X, Sun, A, Pu, J, Pan, L, Tang, G.L.Show

Angew.Chem.Int.Ed.Engl. 65 e22109 e22109 (2026)

PMID: 41761722 DOI: 10.1002/anie.202522109

Primary Citation of related structures

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