9W5L image
Deposition Date 2025-08-01
Release Date 2026-07-08
Last Version Date 2026-07-08
Entry Detail
PDB ID:
9W5L
Keywords:
OXIDOREDUCTASE
Title:
Crystal structure of KRED mutant-Y199A/N149L
Biological Source:
Source Organism(s):
Novosphingobium aromaticivorans DSM 12444 (Taxon ID: 279238)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.94 Å
R-Value Free:
0.24
R-Value Work:
0.18
R-Value Observed:
0.20
Space Group:
P 21 21 21
9W5L validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Short-chain dehydrogenase/red
Gene (Uniprot):Saro_3543
Mutagens:Y199A,N149L
Chain IDs:A, B, C, D
Chain Length:259
Number of Molecules:4
Biological Source:Novosphingobium aromaticivorans DSM 12444
UniProt ID:A4XEP2 Pfam ID:PF13561
Ligand Molecules
DMS
PO4
Primary Citation
Chemo-Enzymatic Synthesis of a Squalamine Intermediate by an Engineered Ketoreductase from Novosphingobium aromaticivorans
Acs Catalysis 16 11618 11630 (2026)
DOI: 10.1021/acscatal.6c03102
Primary Citation of related structures
9W5L
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