ISDA: 9W40

Deposition Date 2025-07-30

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9W40

Keywords:

MEMBRANE PROTEIN

Title:

Structure of adenosine A2BR with an agonist MRS3997

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Escherichia coli (Taxon ID: 562)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.20 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Mutagens:G49D, E50N, A249D, S252D, L272D, I372A, V375I
Chain IDs:A
Chain Length:246
Number of Molecules:1
Biological Source:Homo sapiens

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:366
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF25391

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C (auth: G)
Chain Length:70
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Soluble cytochrome b562,Adeno
Gene (Uniprot):cybC, ADORA2B
Mutagens:M7W,H102I,R106L
Chain IDs:D (auth: R)
Chain Length:607
Number of Molecules:1
Biological Source:Escherichia coli, Homo sapiens

UniProt ID:P0ABE7,P29275 Pfam ID:PF00001

Ligand Molecules