ISDA: 9W0A

Deposition Date 2025-07-24

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9W0A

Keywords:

BIOSYNTHETIC PROTEIN

Title:

Wild-type P450 enzyme-TtpB1

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.48 Å

R-Value Free:

0.25

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 61 2 2

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:TtpB1
Chain IDs:A
Chain Length:399
Number of Molecules:1
Biological Source:Escherichia coli

Ligand Molecules

A1EUF

HEM

Primary Citation

P450-Mediated Dual Cyclization Mechanisms for Pyrroloindoline Unit Formation in Bispyrrolidinoindoline Diketopiperazine Alkaloid Biosynthesis.

Du, Y, Wei, G, Zhou, T.P, Dai, Y, Tian, W, Tang, M, Deng, Z, Wang, B, Qu, X.Show

J.Am.Chem.Soc. 147 45199 45209 (2025)

PMID: 41326270 DOI: 10.1021/jacs.5c14741

Primary Citation of related structures

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