ISDA: 9VY1

Deposition Date 2025-07-20

Release Date 2026-04-29

Last Version Date 2026-05-13

Entry Detail

PDB ID:

9VY1

Keywords:

VIRAL PROTEIN

Title:

Cryo-EM structure of Peste Des Petits Ruminants Virus L Protein bound by Phosphoprotein Tetramer

Biological Source:

Source Organism(s):

peste-des-petits-ruminants virus (Taxon ID: 2593991)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.40 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RNA-directed RNA polymerase L
Chain IDs:A
Chain Length:2183
Number of Molecules:1
Biological Source:peste-des-petits-ruminants virus

UniProt ID:Q5ZER1 EC:2.7.7.48,3.6.1.-,2.7.7.88,2.1.1.-

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Phosphoprotein
Chain IDs:B, C, D, E
Chain Length:509
Number of Molecules:4
Biological Source:peste-des-petits-ruminants virus

UniProt ID:Q5ZER7

Ligand Molecules

Primary Citation

Differential inhibition of Morbillivirus and Henipavirus polymerases by ERDRP-0519 and structure-guided inhibitor optimization.

Xue, L, Gui, J, Gao, S, Gao, X, Chang, T, Pan, H, Tang, J, Zhang, M, Li, Z, Zou, B, Zhao, H, Wang, L, Li, M, Rong, L, Plemper, R.K, Chen, X, He, J, Pei, R, Zhan, P, Xiong, X.Show

Cell ? ? ? (2026)

PMID: 42061399 DOI: 10.1016/j.cell.2026.04.011

Primary Citation of related structures

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