9VY0 image
Deposition Date 2025-07-20
Release Date 2026-04-29
Last Version Date 2026-05-13
Entry Detail
PDB ID:
9VY0
Keywords:
VIRAL PROTEIN
Title:
Cryo-EM Structure of Peste Des Petits Ruminants Virus Polymerase in complex with ERDRP-0519
Biological Source:
Source Organism(s):
peste-des-petits-ruminants virus (Taxon ID: 2593991)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.71 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9VY0 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:RNA-directed RNA polymerase L
Chain IDs:A
Chain Length:2183
Number of Molecules:1
Biological Source:peste-des-petits-ruminants virus
UniProt ID:Q5ZER1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Phosphoprotein
Chain IDs:B, C, D, E
Chain Length:509
Number of Molecules:4
Biological Source:peste-des-petits-ruminants virus
UniProt ID:Q5ZER7
Ligand Molecules
A1EF9
ZN
Primary Citation
Differential inhibition of Morbillivirus and Henipavirus polymerases by ERDRP-0519 and structure-guided inhibitor optimization.
Cell ? ? ? (2026)
PMID: 42061399 DOI: 10.1016/j.cell.2026.04.011
Primary Citation of related structures
9VY0
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