ISDA: 9VXW

Deposition Date 2025-07-20

Release Date 2025-12-31

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9VXW

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of hAQP11 in LMNG

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Aequorea victoria (Taxon ID: 6100)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.30 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Aquaporin-11,sfGFP
Gene (Uniprot):AQP11
Chain IDs:A
Chain Length:537
Number of Molecules:1
Biological Source:Homo sapiens, Aequorea victoria

UniProt ID:Q8NBQ7 Pfam ID:PF00230

Ligand Molecules

D10

Primary Citation

Cryo-EM structure of human AQP11 reveals a trimeric architecture with a large pore.

Suzuki, S, Kamegawa, A, Kozai, D, Nishikawa, K, Irie, K, Fujiyoshi, Y.Show

Sci Adv 12 eaeb5769 eaeb5769 (2026)

PMID: 41616064 DOI: 10.1126/sciadv.aeb5769

Primary Citation of related structures

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