9VVG image
Deposition Date 2025-07-15
Release Date 2026-03-25
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9VVG
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of the erlin1/2 complex purified using GDN and CHS
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.70 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9VVG validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Erlin-1
Gene (Uniprot):ERLIN1
Chain IDs:A, C (auth: M), E (auth: L), F (auth: K), I (auth: J), J (auth: I), L (auth: H), M (auth: G), Q (auth: C), R (auth: B), U (auth: F), W (auth: E), X (auth: D)
Chain Length:297
Number of Molecules:13
Biological Source:Homo sapiens
UniProt ID:O75477 Pfam ID:PF01145
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Erlin-2
Gene (Uniprot):ERLIN2
Chain IDs:B (auth: a), D (auth: m), G (auth: k), H (auth: l), K (auth: i), N (auth: g), O (auth: h), P (auth: j), S (auth: b), T (auth: c), V (auth: f), Y (auth: d), Z (auth: e)
Chain Length:297
Number of Molecules:13
Biological Source:Homo sapiens
UniProt ID:O94905 Pfam ID:PF01145
Ligand Molecules
NA
Primary Citation
The Erlin1/2 complex is a dynamic scaffold for membrane microdomain assembly on the endoplasmic reticulum.
Mol.Cell 86 1362 1376.e5 (2026)
PMID: 41887216 DOI: 10.1016/j.molcel.2026.03.001
Primary Citation of related structures
9VVG
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