9VUR image
Deposition Date 2025-07-13
Release Date 2026-07-22
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9VUR
Keywords:
TRANSCRIPTION
Title:
Crystal Structure of TEAD2 in a covalent complex with LC-TEAD01
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.66 Å
R-Value Free:
0.25
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
C 1 2 1
9VUR validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcriptional enhancer fact
Gene (Uniprot):TEAD2
Chain IDs:A, B
Chain Length:231
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q15562 Pfam ID:PF17725
Ligand Molecules
A1ETO
Primary Citation
In situ double-click chemistry rapid generation of novel and potent covalent TEAD inhibitors
To Be Published ? ? ? (?)
Primary Citation of related structures
9VUR
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