9VTY image
Deposition Date 2025-07-11
Release Date 2026-07-15
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9VTY
Keywords:
PROTEIN FIBRIL
Title:
Cryo-EM structure of ThS-bound ATTRA97S amyloid fibrils extracted from patient-derived abdominal adipose biopsy tissue.
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.30 Å
Aggregation State:
FILAMENT
Reconstruction Method:
HELICAL
9VTY validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transthyretin
Gene (Uniprot):TTR
Chain IDs:A (auth: Q), B, C (auth: N), D (auth: F), E (auth: K), F (auth: H), G (auth: D), H (auth: R), I (auth: L), J (auth: I), K (auth: E), L (auth: G), M (auth: S), N (auth: J), O (auth: P), P (auth: A), Q (auth: C)
Chain Length:127
Number of Molecules:17
Biological Source:Homo sapiens
UniProt ID:P02766 Pfam ID:PF00576
Ligand Molecules
A1ETV
Primary Citation
Structures of dye-bound transthyretin amyloid fibrils from abdominal fat biopsies.
Nat Commun 17 ? ? (2026)
PMID: 42026093 DOI: 10.1038/s41467-026-72441-5
Primary Citation of related structures
9VTY
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