ISDA: 9VTX

Deposition Date 2025-07-11

Release Date 2026-07-15

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9VTX

Keywords:

PROTEIN FIBRIL

Title:

Cryo-EM structure of Congo Red-bound ATTRA97S amyloid fibrils extracted from patient-derived abdominal adipose biopsy tissu

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.00 Å

Aggregation State:

FILAMENT

Reconstruction Method:

HELICAL

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Transthyretin
Gene (Uniprot):TTR
Chain IDs:A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Chain Length:127
Number of Molecules:16
Biological Source:Homo sapiens

UniProt ID:P02766 Pfam ID:PF00576

Ligand Molecules

CGO

Primary Citation

Structures of dye-bound transthyretin amyloid fibrils from abdominal fat biopsies.

Ma, B, Yao, Y, Wang, Q, Zhao, Q, Liu, K, Chen, F, Cheng, H, Zhang, R, Liu, C, Li, D.Show

Nat Commun 17 ? ? (2026)

PMID: 42026093 DOI: 10.1038/s41467-026-72441-5

Primary Citation of related structures

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