ISDA: 9VS2

Deposition Date 2025-07-08

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9VS2

Keywords:

DNA BINDING PROTEIN/DNA

Title:

Crystal structure of FOXC2/NFAT1 complex bound to ARRE3-P DNA

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.65 Å

R-Value Free:

0.27

R-Value Work:

0.22

R-Value Observed:

0.23

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Forkhead box protein C2
Gene (Uniprot):FOXC2
Chain IDs:D (auth: A)
Chain Length:103
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q99958 Pfam ID:PF00250

Polymer Type:polydeoxyribonucleotide
Molecule:ARRE3-P-S
Chain IDs:A (auth: C)
Chain Length:21
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polydeoxyribonucleotide
Molecule:ARRE3-P-AS
Chain IDs:B (auth: D)
Chain Length:21
Number of Molecules:1
Biological Source:Homo sapiens

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nuclear factor of activated T
Gene (Uniprot):NFATC2
Chain IDs:C (auth: N)
Chain Length:287
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q13469 Pfam ID:PF00554, PF16179

Primary Citation

Crystal structure of FOXC2/NFAT1 complex bound to ARRE3-P DNA

Chen, X.J, Chen, Y.H.Show

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