ISDA: 9VM6

Deposition Date 2025-06-27

Release Date 2026-06-03

Last Version Date 2026-06-03

Entry Detail

PDB ID:

9VM6

Keywords:

SIGNALING PROTEIN

Title:

Structure of DOCK6 tetramer

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.27 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Dedicator of cytokinesis prot
Gene (Uniprot):DOCK6
Chain IDs:A, B (auth: C), C (auth: D), D (auth: B)
Chain Length:2053
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q96HP0 Pfam ID:PF11878, PF14429, PF06920, PF20422, PF20421

Ligand Molecules

Primary Citation

Structural basis for auto-inhibition of the Rac1/Cdc42 guanine nucleotide exchange factor DOCK6 by oligomer formation

Kukimoto-Niino, M, Katsura, K, Yoshimura, K, Ishizuka-Katsura, Y, Miyamoto, Y, Yonemochi, M, Hanada, K, Yamauchi, J, Wong, R.W, Shirouzu, M.Show

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Primary Citation of related structures

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