9VFL image
Deposition Date 2025-06-11
Release Date 2026-06-17
Last Version Date 2026-06-17
Entry Detail
PDB ID:
9VFL
Keywords:
ONCOPROTEIN
Title:
Crystal structure of PLCG1 SH2(C) domain with a triple Tyr phosphorylated peptide derived from NTRK1
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.40 Å
R-Value Free:
0.25
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 41 21 2
9VFL validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:1-phosphatidylinositol 4,5-bi
Gene (Uniprot):PLCG1
Chain IDs:A, C, E, G, I, K, M, O, Q, S, U, W
Chain Length:96
Number of Molecules:12
Biological Source:Homo sapiens
UniProt ID:P19174 Pfam ID:PF00017 EC:3.1.4.11
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:High affinity nerve growth fa
Gene (Uniprot):NTRK1
Chain IDs:B, D, F, H, J, L, N, P, R, T, V, X
Chain Length:16
Number of Molecules:12
Biological Source:Homo sapiens
UniProt ID:P04629 EC:2.7.10.1
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PTR B TYR modified residue
Ligand Molecules
CL
PO4
Primary Citation
Crystal structure of PLCG1 SH2(C) domain with triple phosphorylated peptide derived from NTRK1
To Be Published ? ? ? (?)
Primary Citation of related structures
9VFL
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