9VE3 image
Deposition Date 2025-06-09
Release Date 2026-02-04
Last Version Date 2026-08-19
Entry Detail
PDB ID:
9VE3
Keywords:
NUCLEAR PROTEIN
Title:
The MIDN Catch-IRF4 (V2L) fusion protein
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli (strain b / bl21-de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.10 Å
R-Value Free:
0.26
R-Value Work:
0.22
R-Value Observed:
0.22
Space Group:
P 65 2 2
9VE3 validation report missing
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Midnolin,Interferon regulator
Gene (Uniprot):MIDN, IRF4
Mutagens:V216L
Chain IDs:A
Chain Length:68
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q504T8,Q15306
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Midnolin
Gene (Uniprot):MIDN
Chain IDs:B
Chain Length:73
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q504T8
Primary Citation
Biochemical and structural studies of the midnolin Catch domain bound with both wild-type and mutant IRF4 peptides reveal the molecular basis for its broad substrate specificity.
Acta Biochim.Biophys.Sin. 58 1235 1249 (2026)
PMID: 41531205 DOI: 10.3724/abbs.2026002
Primary Citation of related structures
9VE3
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