ISDA: 9VE2

Deposition Date 2025-06-09

Release Date 2026-06-17

Last Version Date 2026-06-17

Entry Detail

PDB ID:

9VE2

Keywords:

OXIDOREDUCTASE

Title:

Crystal Structure of Human Peroxiredoxin I in Complex with Fluvastatin

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.80 Å

R-Value Free:

0.19

R-Value Work:

0.15

R-Value Observed:

0.15

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Peroxiredoxin-1
Gene (Uniprot):PRDX1
Chain IDs:A, B
Chain Length:175
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q06830 Pfam ID:PF00578, PF10417 EC:1.11.1.24

Ligand Molecules

115

Primary Citation

Fluvastatin protects Leydig cells in orchitis through direct activation of Peroxiredoxin 1

Zhang, H, Xu, H.Show

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Primary Citation of related structures

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