ISDA: 9VDU

Deposition Date 2025-06-09

Release Date 2026-05-20

Last Version Date 2026-05-20

Entry Detail

PDB ID:

9VDU

Keywords:

MEMBRANE PROTEIN

Title:

Crystal structure of voltage-gated sodium channel NavAb N49K/L176F DC230 mutant

Biological Source:

Source Organism(s):

Aliarcobacter butzleri (strain RM4018) (Taxon ID: 367737)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.40 Å

R-Value Free:

0.30

R-Value Work:

0.25

R-Value Observed:

0.25

Space Group:

I 4 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ion transport protein
Gene (Uniprot):Abu_1752
Mutagens:N49K/L176F
Chain IDs:A
Chain Length:232
Number of Molecules:1
Biological Source:Aliarcobacter butzleri (strain RM4018)

UniProt ID:A8EVM5 Pfam ID:PF00520

Ligand Molecules

1N7

PX4

Primary Citation

The structural dynamics and molecular coupling in the slow inactivation of a prokaryotic voltage-gated sodium channel

Irie, K, Han, S, Applewhite, S, Maeda, Y.K, Vance, J, Wang, S.Show

Biorxiv ? ? ? (2026)

DOI: 10.1101/2025.08.14.670348

Primary Citation of related structures

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