ISDA: 9V8X

Deposition Date 2025-05-30

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9V8X

Keywords:

MEMBRANE PROTEIN

Title:

membrane protein S6A8 with Crea

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.85 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Sodium- and chloride-dependen
Gene (Uniprot):SLC6A8
Chain IDs:A
Chain Length:635
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P48029 Pfam ID:PF00209

Ligand Molecules

CRN

Primary Citation

Structural insights into the substrate uptake and inhibition of the human creatine transporter (hCRT).

Yuan, X, Yin, J, Liu, C, Chen, X, Chen, M, Wang, Y, Yang, Z, Wang, Y, Jiang, L, Zhou, N, Wang, X, Liu, B, Ma, Z, Wang, K, Li, H, Zhang, S, Shang, Y, Yang, M.Show

Proc. Natl. Acad. Sci. U.S.A. 122 e2426135122 e2426135122 (2025)

PMID: 40892912 DOI: 10.1073/pnas.2426135122

Primary Citation of related structures

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